Classification of Diabetic Nephropathy

Stage 1: It is characterized by increased glomerular filtration rate and augment of the kidney volume. During this period, pathological changes are in coordination with blood sugar level and the disease is still reversible with insulinization.

Stage 2: Urinary albumin excretion may increase after strenuous exercise but can recover. However, glomerular structure has begun to change with thickened glomerular basement membrane and increased mesangial matrix. Glomerular filtration rate is often higher than normal and in coordination with blood sugar level. Throughout the first two stages, glomerular filtration rate increases and urinary albumin excretion is still normal, for which it can’t be called as Diabetic Nephropathy.

Stage 3: It is called as early stage Diabetic Nephropathy. Urinary albumin excretion rate is 20-200ug/min. Other symptoms include slight blood pressure increase and onset of glomeruli dilapidation.

Stage 4: Clinical and obvious pathological changes can be found. During the stage, there appear large quantities of proteinuria (more than 3.5g/24h), swelling, and hypertension.

Stage 5: It is characterized by end stage renal failure, which results from progressive and continuous declination of renal functions.

The key to dealing with the condition of the patient is to repair the damaged kidneys. Clinical combination of traditional Chinese medicine and western medicine based on syndrome differentiation can effectively change the condition. On this respect, Micro-Chinese Medicine Osmotherapy has been proved by clinical practice to be the most powerful. With effective substances inside, Micro-Chinese Medicine Osmotherapy can gradually increase effective blood flow, change the hypoxia and ischemia condition and get rid of the immune complex piled in the kidneys leading to renal fibrosis so as to repair damages renal functions.

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