An Introduction for Renal Biopsy


1. Renal biopsy determines the treatment method for kidney disease. In clinical practice, a complete diagnosis of kidney disease include three aspects: clinical diagnosis, pathological diagnosis and kidney disease diagnosis. Diseases of the same clinical diagnosis may belong to different pathological types, which may further determine the treatment principles. Therefore, renal biopsy will help to judge the specific pathological change type and give effective treatments.

2. The manifestations of the renal biopsy will determine the prognosis. Kidney disease progression is a process of renal fibrosis caused by such inducing factors as cold, fatigue or infections and during the process, large amounts of immune complex accumulate in the kidneys, which does damage to renal intrinsic cells, glomeruli, renal tissues and kidney vessels. The degree of renal fibrosis and changes in the kidneys can be reflected through renal biopsy, which can help to analyze the illness condition.

Take patients with Nephrotic Syndrome for example: After renal biopsy, some may be diagnosed as Membranous Nephropathy, while some others may be diagnosed as Mesangial Proliferative Nephritis. In addition, although both of the two belong to Nephrotic Syndrome by clinical diagnosis, the one manifested as Membranous Nephropathy in pathological change will have poorer prognosis.


Although renal biopsy is mature enough, it is still a traumatic examinaiton and many complications such as hematuria and hematoma. And some patients who have bleeding tendency are not suitable for taking renal biopsy. In some other cases such as high blood pressure, pregnancy, obesity, heart failure, severe anemia, mental disorders, renal biopsy should be taken only after all these risk factors are corrected.

In conclusion, renal biopsy is a very valuable but a traumatic examination. Whether renal biopsy should be taken or not should be considered and valued by the doctors seriously.

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