Why Does Diabetes Cause Azotemia
Azotemia is characterized by high levels of NPN such as creatinine, urea, various body waste compounds and other nitrogen-rich compounds in the blood. Azotemia is largely related to the kidney damage.
Healthy kidneys are able to remove the wastes and excessive fluid from the blood. If they are damaged, they fail to remove these wastes produced by the body. As a result, the wastes such as urea, creatinines build up in the body. This is very harmful to people.
Diabetes and kidney problems
Diabetes is disease which is characterized by high levels of sugar in the blood. Long-term high blood sugar can damage any part of the body causing diabetic complications including kidney disease.
High blood sugar increases blood-flow through the kidneys. If blood sugar is controlled in short time, kidneys can recover from overwork. However, if blood sugar is out of control, over time kidneys work hard and have an irreversible damage. And then the insufficiency of filtering occurs.
Kidney disease is common and can be found in up to 23% of patients with diabetes. Diabetes is often associated with CKD, and for 45% of patients who receive dialysis therapy, diabetes is the primary cause of their kidney failure.
At the early stage, there are no obvious symptoms only increased GFR. Over time, microalbumin is found in the urine which is the earliest sign of kidney damage in diabetics. If untreated immediately, it develops into stage 3 or 4 in which patients may experience more serious symptoms such as nausea, vomiting, proteinuria, high blood pressure, fatigue, headache, heart problems, etc. At the last, end-stage renal disease occurs. At that time, dialysis or kidney transplant is coming. It is very hard to reverse the disease. Therefore, early detection and treatment is very important. Shijiazhuang Kidney Disease Hospital suggests that diabetics receive annual examination to find whether your kidneys are damaged at first.
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