Causes and Symptoms of Nephrotic Syndrome

In our body, Proteins are responsible for soaking up water from tissues. Normally, proteins are blocked from leakage by a kidney filtrating units called as glomeruli. When glomeruli get damaged, the protein is excreted outside with urine, causing reduction of plasma protein and leading to swelling in face, eyes, feet and hands. Main causes and symptoms of Nephrotic Syndrome are shown as follows.

Causes of Nephrotic Syndrome

1. Primary kidney diseases

Primary kidney diseases that can cause Nephrotic Syndrome mainly include Primary Glomerular Disease, Acute or Chronic Glomerulonephritis.

2. Systemic diseases

Systemic diseases such as diabetes mellitus, systemic lupus erythematosus, and multiple myeloma can affect multiple organs and systems in the body, one among them being kidney.

4. Infections

In some cases, Nephrotic Syndrome can be resulted or affected by infections such as malaria, infective endocarditis, hepatitis B and C, syphilis, streptococcal throat infection and so on.

3. Allergy

Nephrotic Syndrome tend to appear in individuals with family history or prior history of allergy.

5. Medicine toxicity

Certain modern medicines such as antibiotics, antihypertensive medicines, gold preparations may induce Nephrotic Syndrome in sensitive individual.

Symptoms of Nephrotic Syndrome may include

1. Edema

Nephrotic Syndrome is characterized by proteinuria, hypoalbuminemia, and hyperlipidemia. The first noticeable outcome of all these metabolic deviations is edema or bloating of the body.

2. Oliguria

Oliguria means reduction in the quantity of normal urine.

3. Hematuria

Occasionally, patients with Nephrotic Syndrome presents suffer from gross hematuria.

4. Respiratory distress

If ascites appears obviously, patients usually suffer from respiratory distress, with breathing difficulty or rapid breathing.

5. High blood pressure

Elevated blood pressure is common among patients with Patients of Nephrotic Syndrome, whether young or old.

In addition, caused by swelling in bowel wall, patients commonly present diarrhea. Nephrotic Syndrome patients also commonly have loss of appetite, feel fatigued, and appear pale.

Above all are the causes and symptoms of Nephrotic Syndrome, hope it has helped help you understand the disease better.

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