Clinical manifestations of diabetic kidney disease (diabetic nephropathy)

Diabetic nephropathy is the medical term for the type of kidney disease that occurs in diabetes. Diabetic kidney disease is one of diabetic complications that is due to long-term blood pressure. Long-term blood pressure leads to changes in small blood vessels that can causes damage of kidneys. This kidney damage can develop into renal failure. Diabetic kidney disease start 5-10 years onset of diabetes. The early symptom or sign is the proteinuria.

What are the clinical manifestations of diabetic kidney disease?

Healthy kidneys are very important organs which can remove wastes and excessive fluid from the blood to maintain healthy. They play important role in controlling blood pressure, and produce hormone,erythropoietin, that stimulates the bone marrow to manufacture red blood cells.

When your kidneys are damaged due to high blood pressure, some symptoms will occur as the followings.

In the early stage of diabetic kidney disease, your GFR will increase, which is the renal function change.

At the very beginning, it is intermittent proteinuria and then persistent proteinuria occurs. Diabetic kidney disease attacks after 10 or so onset of diabetes. Gross hematuria rarely occurs.

As the proteinuria is over 3.5g per day, edema may occur. Approximate 5-10% patients have nephrotic syndrome, namely a large amount of proteinuria, edema, hypoproteinemia.

High blood pressure occurs in late stage of type 1 diabetes, but at any time in type 2 diabetics. High blood pressure deteriorates kidney disease.

Rena failure comes. With condition aggravating, GFR decreases, resulting in azotemia. Diabetic kidney disease in most people develops into renal failure.

Early treatment of diabetic kidney disease is the key to delay renal failure or reverse the condition. If you have any other question about diabetes, you can consult our experts online. We are glad to help you!

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