Case Study Type 2 Diabetes
Patient: Wang tao, Male, 64 years old, Type 2 Diabetes
Main complcaints: increased thirst, increased hunger, frequent urination, and loss of weight for about 24 years, and retinopathy for about 6 years.
Medical history: The patient had a history of hypertension for 35 years, and he persists in taking medicines to have the blood pressure under control, about 150/80mmHg. Both his grandpa and uncle had Diabetes. He was detected as Type 2 Diabetes about twenty four years ago. The doctors prescribe some oral glybenzcyclamide, and DMBG to control his blood sugar. Ten years later, his blood sugar got out of control, and then he started subcutaneous injection of insulin before every meal. In recent years, the creatinine and urine protein was increasing, and the swelling in the lower limbs and eyelids was aggravating.
Physical examination when hospitalized: Blood pressure: 160/85mmHg, no anemia, normal heart and lung, severe swelling of the lower limbs.
Fasting Blood-Glucose: 8.4mmol/L, blood glucose after meals: 12.5mmol/L.
Blood routine test: HGB：148g/L, RBC：4.68×1012/L
Urine Protein Quantitation in 24 hrs: 0.62g/24h.
Serum creatinine: 287umol/L，BUN：5.67mmol/L，Uric Acid：293mmol/L
Diagnosis: Type 2 Diabetes, Diabetic Nephropathy, primary hypertension
Treatment procedure: After he was hospitalized, he was first given Micro-Chinese Medicine Osmotherapy to improve the blood circulation, and other symptoms. Stem Cell Transplant was transfused about 10 days later. After a week of stem cell transplant, the use of insulin was reduced. Symptoms of swelling and his high blood pressure were also improved. Two weeks later, the dose of insulin decreased from the former 33u daily to 24u daily.
Expert comments: For this patient, he has hypertension for many years. Micro-Chinese Medicine Osmotherapy is effective to improve blood circulation of the whole body so after a few days’ treatment, his blood pressure become controlled. The mechanisms for stem cell transplant to treat Diabetes are as follows:
First, Type 2 Diabetes is caused by the damaged pancreas islet β cells. After the stem cells are transfused to the body, the damaged system can be repaired and rebuilt and gradually the function of the pancreas can be recovered to maintain the normal banlance.
Second, stem cells can directly repair the damaged pancreas islet β cells, and promote the regeneration of endogenous islet cells, so the secretion of the insulin will be increased.
Third, bioactivator will be secreted to repair the damaged pancreas islet. Stem cells can secrete many bioactivator and growth factors, such as transforming growth factor B, vascular endothelial growth factor etc. Transforming growth factor is a multi-functional factor, which can repair the damaged tissues, promote the pancreas islet proliferate and the regeneration of the secretory cells.
Fourth, stem cells can increase the sensitivity trans-glycoprotein, promote the combination of the insulin receptor and insulin, and decrease the resistance of the insulin so as to achieve the therapeutic effect.
After many cases of the stem cell transplant to the patients with Diabetes, all the Diabetic patients have improvements in their condition. The short-term effect is the use of insulin will be reduced. With the continuous repair and recover of the islets functions, blood sugar will gradually return to normal. If you are a patient with Diabetes, an early treatment is needed so it will not develop further into Diabetic Nephropathy or Kidney Failure.
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